NFPA 560-2007 Standard for the Storage Handling and Use of Ethylene Oxide for Sterilization and Fumigation (Effective Date 12 20 2006).pdf

1、NFPA 560 Standard for the Storage, Handling, and Use of Ethylene Oxide for Sterilization and Fumigation 2007 Edition NFPA, 1 Batterymarch Park, Quincy, MA 02169-7471 An International Codes and Standards Organization IMPORTANT NOTICES AND DISCLAIMERS CONCERNING NFPA DOCUMENTSNOTICE AND DISCLAIMER OF

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22、PA 560Standard for theStorage, Handling, and Use of Ethylene Oxidefor Sterilization and Fumigation2007 EditionThis edition of NFPA 560, Standard for the Storage, Handling, and Use of Ethylene Oxide forSterilization and Fumigation, was prepared by the Technical Committee on Industrial and Medi-cal Ga

23、ses. It was issued by the Standards Council on December 1, 2006, with an effective dateof December 20, 2006, and supersedes all previous editions.This edition of NFPA 560 was approved as an American National Standard on December 20,2006.Origin and Development of NFPA 560In June 1990, a request was m

24、ade by a manufacturer of ethylene oxide to develop a newstandard for the storage, handling, and use of ethylene oxide for sterilization and fumigation.This request addressed the replacement of the nonflammable mixture of ethylene oxide andfreon with pure ethylene oxide, which was occurring concurren

25、t with the reduced use offreon for environmental reasons. The request was reviewed by the NFPA Standards Council,which published a notice in the August 1990 edition of Fire News asking for public input on therecommendation.At its January 1991 meeting, the NFPA Standards Council approved the request

26、and the devel-opment of the standard was assigned to the NFPATechnical Committee on Industrial and MedicalGases (IMGAS). The IMGAS Committee established a task force on ethylene oxide, which devel-oped a draft standard that was made available for public review. Notice of its availability waspublishe

27、d in the December 1993/January 1994 edition of Fire News with a public proposal closingdate of January 21, 1994. The IMGAS Committee reviewed the proposals, and the Committeesreport was published in the 1995 Annual Meeting Report on Proposals. Further revisions werepublished in the 1995 Annual Meeti

28、ng Report on Comments.The 2002 edition contained requirements in Chapter 11 that addressed the use of oxidiz-ing emission control devices. These requirements were based on the recommendations of aNIOSH report generated after several incidents occurred that involved oxidizing emissioncontrol device o

29、perations.The 2002 edition was also revised to conform to the new Manual of Style for NFPATechnicalDocuments requirements.The 2007 edition includes the following changes: Elimination of the concept of special rooms to achieve consistency with NFPA 5000,Building Construction and Safety Code Addition

30、of the definition of Sterilization Building Correlation of gas storage requirements with NFPA 55, Standard for the Storage, Use, andHandling of Compressed Gases and Cryogenic Fluids in Portable and Stationary Containers, Cylinders,and Tanks Updated definitions5601Technical Committee on Industrial an

31、d Medical GasesMichael W. St. Clair, ChairOstrander, OH URep. NFPA Industrial Fire Protection SectionWilliam J. Satterfield, III, SecretaryHydrogen Safety, LLC/Rode the installation of associated storage, piping, and distribution equipment; and operating practices.The Committee also has a technical

32、responsibility for contributions in the same areas for medical gases andclean rooms.5602 STORAGE, HANDLING, AND USE OF ETHYLENE OXIDE FOR STERILIZATION AND FUMIGATION2007 EditionContentsChapter 1 Administration . 56041.1 Scope . 56041.2 Purpose 56041.3 Alternate Materials, Equipment, andProcedures 5

33、6041.4 Retroactivity 56041.5 Equivalency . 5604Chapter 2 Referenced Publications . 56042.1 General 56042.2 NFPA Publications . 56042.3 Other Publications 56042.4 References for Extracts in MandatorySections 5605Chapter 3 Definitions 56053.1 General 56053.2 NFPA Official Definitions 56053.3 General D

34、efinitions . 5605Chapter 4 Receiving and Unloading EthyleneOxide Containers . 56054.1 Scope . 56054.2 Procedures 5606Chapter 5 Storage of Ethylene Oxide 56065.1 General 56065.2 Indoor Storage . 56065.3 Storage Outside of Buildings . 5606Chapter 6 Piping Systems . 56066.1 Scope . 56066.2 Materials fo

35、r Piping, Valves, and Fittings . 56076.3 Preparation for Dismantling of Piping . 56076.4 Valves . 56076.5 Testing . 56076.6 Identification . 5607Chapter 7 Gas Dispensing Areas . 56077.1 General 56077.2 Ethylene Oxide Containers . 56077.3 Nitrogen System . 56077.4 Vaporizer 56077.5 Liquid Ethylene Ox

36、ide Piping . 5607Chapter 8 Operations 56088.1 Operating Procedures Manual . 56088.2 Sterilizer Operation 56088.3 Area Monitoring for Ethylene Oxide . 56088.4 Emergency Stop . 5608Chapter 9 Electrical Installation . 56089.1 Area Electrical Classification . 56089.2 Static Electricity Control . 56089.3

37、 Grounding Requirements . 5608Chapter 10 Sterilizer Construction 560810.1 Vessel . 560810.2 Rotating Equipment 560810.3 Pressure Relief Device 5608Chapter 11 Disposal and Emissions . 560811.1 Scope . 560811.2 Wet Scrubbers 560811.3 Flare Stacks . 560811.4 Catalytic Converter 560811.5 Oxidizing Emiss

38、ion Control Devices 5609Chapter 12 Maintenance 560912.1 General Requirements . 560912.2 Maintenance Manuals 5609Chapter 13 Construction 560913.1 Scope . 560913.2 Separate Structures or Buildings 5609Chapter 14 Fire Protection 560914.1 Sprinklers . 5609Annex A Explanatory Material . 5609Annex B Signi

39、ficant Properties of EthyleneOxide 56010Annex C Informational References . 56012Index . 560135603CONTENTS2007 EditionNFPA 560Standard for theStorage, Handling, and Use of EthyleneOxide for Sterilization and Fumigation2007 EditionIMPORTANT NOTE: This NFPA document is made available foruse subject to

40、important notices and legal disclaimers. These noticesand disclaimers appear in all publications containing this documentand may be found under the heading “Important Notices and Dis-claimers Concerning NFPA Documents.” They can also be obtainedon request from NFPA or viewed at www.nfpa.org/disclaim

41、ers.NOTICE: An asterisk (*) following the number or letter des-ignating a paragraph indicates that explanatory material on theparagraph can be found in Annex A.Changes other than editorial are indicated by a vertical rulebeside the paragraph, table, or figure in which the change oc-curred. These rul

42、es are included as an aid to the user in identify-ing changes from the previous edition. Where one or more com-plete paragraphs have been deleted, the deletion is indicated bya bullet ( ) between the paragraphs that remain.A reference in brackets following a section or paragraphindicates material th

43、at has been extracted from another NFPAdocument. As an aid to the user, the complete title and edition ofthe source documents for extracts in mandatory sections of thedocument are given in Chapter 2 and those for extracts in infor-mational sections are given in Annex C. Editorial changes to ex-tract

44、ed material consist of revising references to an appropriatedivision in this document or the inclusion of the document num-ber with the division number when the reference is to the origi-nal document. Requests for interpretations or revisions of ex-tracted text shall be sent to the technical committ

45、ee responsiblefor the source document.Information on referenced publications can be found inChapter 2 and Annex C.Chapter 1 Administration1.1 Scope. This standard shall apply to the storage and han-dling of ethylene oxide in portable containers for its use insterilization and fumigation. It also sha

46、ll apply to flammablemixtures of ethylene oxide with other chemicals.1.1.1 This standard shall not apply to the following:(1) Nonflammable mixtures of ethylene oxide with otherchemicals(2) Ethylene oxide manufacturing facilities, and container fill-ing, refilling, or transfilling facilities(3)*The o

47、ff-site transportation of portable containers of ethyl-ene oxide(4) Facilities using ethylene oxide as a chemical feedstock(5) Ethylene oxide in chambers 0.283 m3(10 ft3) or less involume, or for containers holding 200 g (7.05 oz) of eth-ylene oxide or less1.2 Purpose. The purpose of this document i

48、s to give require-ments to reduce the occurrence of fire explosions in the use ofethylene oxide sterilizing systems.1.3 Alternate Materials, Equipment, and Procedures. The provi-sions of this standard are not intended to prevent the use of anymaterial, method of construction, or installation procedu

49、re notspecifically prescribed by this standard, provided any such alter-nate is acceptable to the authority having jurisdiction (see 3.2.1).The authority having jurisdiction shall require that sufficient evi-dence be submitted to substantiate any claims made regardingthe safety of such alternates.1.4 Retroactivity. The provisions of this standard reflect a con-sensus of what is necessary to provide an acceptable degree ofprotection from the hazards addressed in this standard at thetime the standard was issued.