KS I ISO 16702-2009 Workplace air quality-Determination of total organic isocyanate groups in air using 1-(2-methoxyphenyl)piperazine and liquid chromatography《工作场所空气质量 用1-(2-甲氧基苯基.pdf

1、 KSKSKSKS KSKSKSK KSKSKS KSKSK KSKS KSK KS KS I ISO 16702 1-(2-) KS I ISO 16702 :2009 2009 12 18 http:/www.kats.go.krKS I ISO 16702:2009 : ( ) ( ) ( ) ：(ISO/TC146) () ( ) () : (http:/www.standard.go.kr) ： ：2001 12 6 ：2009 12 18 2009-0830 ： ： (ISO/TC146) ( 02-509-7266) (http:/www.kats.go.kr). 10 5 ,

2、. KS I ISO 16702:2009 1-(2-) Workplace air qualityDetermination of total organic isocyanate groups in air using 1-(2-methoxyphenyl)piperazine and liquid chromatography 2007 2 ISO 16702, Workplace air qualityDetermination of total organic isocyanate groups in air using 1-(2-methoxyphenyl)piperazine a

3、nd liquid chromatography , . 1 (NCO) . . (TDI)(2,4-, 2,6- diisocyanatotoluene), (NDI)(1,5-diisocyanatonaphthalene), (4-)MDI, di-(4-isocyanatophenyl)methane . (IPDI, 1-isocyanato-3-isocyanatomethyl-3,5,5-trimethylcyclohexane) (hydrogenated MDI, HMDI), 1,6-diisocyanatohexane(HDI)( 1,6-hexamethylenedii

4、socyanate ) . ( , methylisocyanate, ethyl isocyanate, phenyl isocyanate, hexyl isocyanate) , . polyisocyanates, homopolymers, oligomers prepolymers polyols diisocyanate monomer . Polymeric diisocyanates , , . . MDI, HDI, TDI, 1 . IPDI, HMDI, NDI . . , monomeric diisocyanates, oligomeric, prepolymeri

5、c polymeric diisocyanates, monoisocyanates . . 2 , KS I ISO 16702:2009 2 , . 3 mono-isocyanates , 37 mm . . , . . 0.5 8 . . , . . , . 15 L 0.1 g/m 3 140 g/m 3 . 6 3 10 , 0.001 g 0.004 g . 15 L , 0.07 g/m 3 0.3 g/m 3 . 2 . . ( ) . KS A ISO 57252, ( )2： EN 1232, Workplace atmospheresPumps for personal

6、 sampling of chemical agentsRequirements and test methods 3 , . 3.1 3.1.1 (isocyanate) (nitrogen carbon oxygen) 3.1.2 (monomer) dimer, trimer, oligomer, polymer . monoisocyanates( methyl isocyanate), diisocyanates di(4-isocyanatophenyl) KS I ISO 16702:2009 3 methane (MDI), triisocyanates tri(4-isocy

7、anatophenyl)methane 3.1.3 (diisocyanate) 3.1.4 (oligomer) 3.1.5 , - (polyisocyanate, oligo-isocyanate) 3.1.6 (prepolymer) di- poly-isocyanate polyol . . 3.2 3.2.1 (time-weighted average concentration) 3.2.2 (field blank) . 3.3 (uncertainty) , . ISO/EC Guide 98：1995 52.2.3 1 , ( ) . 2 . . . A B . 4 .

8、 , MP 1-(2-methoxyphenyl) piperazine KS I ISO 16702:2009 4 (MP) . , MP . , MP ( ) MP ( ) 1-(2-methoxyphenyl) piperazine(MP) . . (UV) (EC) (HPLC) . (peak) (EC) (UV) , (DAD) (MS) . MP ( HDI, MDI, TDI isomers), (UV) . , , , , (EC) . . 5 . 5.1 MP 1-(2-methoxyphenyl)piperazine ( 98 %, ) . 5.2 , . . . . 5

9、.3 5.3.1 MP 50 mg 100 mL . . 260 M 10 mL 100 mL . 5.3.2 (A) 0.25 g MP 25 mL . . 5.3.3 . 5.4 KS I ISO 16702:2009 5 5.4.1 0.1 g(HDI, TDI, MDI 1 mmol) MP 0.6 g(3 mmol) 1 . , ( Whatman No 1 2 ) . 60 , . , , . . . 5.4.2 MDI HMDI . (MDI 0.25g, HMDI 2 mmol NCO) (25 mL) (50 mL) 1-(2-methoxyphenyl) piperazin

10、e(1 g,5 mmol) . , 500 mL . . , . . , , . 5.4.3 5.4.3.1 100 mL . HPLC . NCO 0.01 g/mL 1.0 g/mL . 5.4.3.2 . 5.4.3.3 1 NCO (1) . U NCO U NCO M n M (1) U： ( g/mL) M NCO：NCO n ： M U： 5.5 7 6 . 2,4-TDI 2,6-TDI 90 KS I ISO 16702:2009 6 ( 73 % 81 % ) 8 . MDI 6 HSE Workplace Analysis Scheme for Proficiency (

11、WASP) 1 . MP Desmodur N 3390 27 (9111) %, 0.1, 1, 2 g/ 9 . 5.6 HPLC . , . “” monomeric diisocyanates MP . polymeric isocyanate MP , “” . polymeric MP , MP . 5.6.1 “” monomeric diisocyanates mono-isocyanates “ ” . 5 g 1 L . pH 6.0 . 550 mL (450 mL) , 45 % 55 % . 5.6.2 “” “ ” . 5 g 1 L . pH 6.0 . 400

12、mL (600 mL) , 60 % 40 % . 5.7 (Calibration blend atmosphere) . ISO 6145( ) . . 6 (8.2). . 6.1 . , . , . . 6.2 KS I ISO 16702:2009 7 25 mm . 95 % , . MP GF/A . 6.3 MDHS14/3 10 . (Institute of Occupational Medicine) 25 mm (head) . / 25 mm Swinnex . 6.4 . . “ ” . 6.5 EN 1232 . . 6.6 900 mm , , . (fluor

13、oelastomer) . (loss) , ( ) . 6.7 , 5 % . . 10 . . 6.8 LC 0.5 m . LC 0.5 m syringe . 6.9 ( ) , , , . 6.10 KS I ISO 16702:2009 8 (UV) (EC) . EC . . . HPLC EC . EC (loop) (50 mV ) . (pulse dampener) LC () (S/N) . 6.11 . 7 . 7.1 , . ( ) . 7.2 , . 8 . 7.3 () ( ) . , . . . 7.4 () 7.4.1 1-(2-methoxyphenyl)

14、piperazine 0.25 g 25 mL . . A (5.3.2 ). , 25 mm . . A 200 L . . . , . “ ” . 6 . 7.4.2 () . KS I ISO 16702:2009 9 . , . 5 % . , . 7.5 () 10 mL . . . 7.6 ( ) 7.6.1 . , . , . . (0) . 7.6.2 2.0 L/min . 20 L 900 L . , 2 ( 2 ). , . . 5 % , . . , 5 % . 7.7 ( ) 7.7.1 . . ( ) . . , 1 m . , ( 10 m) . ( 13 ). 7.7.2 KS I ISO 16702:2009 10 1 L/min . / . . , - - . . 7.8 5 % , . ( ), 5 %