6242018213 10 301. 2. 3. Batch culture4. 5. 6. 7. 8. Catabolite repression9. 10. Unculturable microorganism4 5201. Bacillus subtilis2. Aspergillus oryzae30423. Corynebacterium glutamicum4.Bacillus thuringiensis5. Penicillium chrysogenum10 6 601. G+G22. 3. 5% 1.5% 0.5%0.1% 2% pH5.0 123 200 mL4. 5. 6. 12320 2 401. 2. DNA