1、大学四级-127 及答案解析(总分：693.00，做题时间：90 分钟)一、BPart Writing(总题数：1，分数：106.00)1.1据称，在你所在的社区将建立一个大型的购物中心 2发表你的意见并说出支持或反对的理由 BA Shopping Mall in the Neighborhood/B（分数：106.00）_二、BPart Reading (总题数：1，分数：70.00)BGenetic Testing/BGenetic testing is transforming medicine and the way families think about their health.
2、 As science uncovers the complicated secrets of DNA, we face difficult choices and new challenges. About Genetic TestingThe year was 1895 and Pauline Gross, a young actress, was scared. Gross knew nothing about the human-genome (基因组，染色体组) project-such medical triumphs, but she did know about a nasty
3、 disease called cancer, and it was running through her family. “Im healthy now,“ she often told Dr. Aldred Warthin a pathologist at the University of Michigan, “but I fully expect to die an early death.“At the time, Grosss prediction was based solely on observation: family members had died of cancer
4、; she would, too. Today, more than 100 years later, Grosss relatives have a much more clinical option: genetic testing. With a simple blood test, they can peer into their own DNA, learning-while still perfectly healthy-whether they carry an inheritable gene mutation (突变) that has dogged their family
5、 for decades and puts them at serious risk.BTake the Testing/BTesting is just one piece of the genomic revolution. A major goal is to create new sophisticated therapies that home in on a diseases biological source, then fix the problem. Already, genes are helping to predict a patients response to ex
6、isting medications. A prime example, taken by Dr. Wylie Burke of the University of Washington, is a variant of a gene called TPMT, which can lead to life-threatening reactions to certain doses of chemotherapy (化学疗法). A genetic test can guide safe and appropriate treatment. Two genes have been identi
7、fied that influence a persons response to some anti-blood-clotting drug. And scientists are uncovering genetic differences in the way people respond to other widely used medications, like antidepressants (搞抑郁药).Knowing a patients genotype, or genetic profile, may also help researchers uncover new pr
8、eventive therapies for sticky diseases. At Johns Hopkins University School of Medicine, Dr. Christopher Ross has tested several compounds shown to slow the progression of Huntingtons in mice. Now he wants to test them in people who are positive for the Huntingtons mutation but have not developed sym
9、ptoms-a novel approach to clinical drug trials, which almost always involve sick people seeking cures. “Were using genetics to move from treating the disease after it happens,“ he says, “to preventing the worst symptoms of the disease before it happens.“Its not just their own health that people care
10、 about. There is also the desire to get rid of disease from the family tree. Therefore, the future is what drives many adults to the clinic. The gene tests currently offered for certain diseases, like breast cancer, affect only a small percentage of total cases. Inherited mutations contribute to jus
11、t 5 to 10 percent of all breast cancers. But the impact on a single life can be huge. The key: being able to do something to ward off disease. “Genetic testing offers us profound insight,“ says Dr. Stephen Gruber, of the University of Michigan. “But it has to be balanced with our ability to care for
12、 these patients.“Genetic testing today starts at the earliest stages of life. Couples planning to have children can be screened prior to conception to see if they are carriers of genetic diseases; prenatal (产前) tests are offered during pregnancy, and states now screen newborns for as many as 29 cond
13、itions, the majority of them genetic disorders. For Jana and Tom Monaco, of Woodbridge, Va. , early testing has made an enormous difference in the lives of their children. Their journey began in 2001, when their seemingly healthy third child, 3-year-old Stephen, developed a life-threatening stomach
14、virus that led to severe brain damage. His diagnosis: a rare but treatable disease called isovaleric acidemia (IVA). Unknowingly, Jana and her husband were carriers of the disease, and at thc time, IVA was not included in newborn screening. The Monacos had no warning whatsoever.BNot Take the Testing
15、/BGenetic testing, exciting as it may seem, isnt always the answer. When Wendy Uhlmann, a genetic counselor at the University of Michigan, teaches medical students, she flashes two slides on a screen side by side. One says ignorance is bliss (福佑). The other: knowledge is power. Thats because the val
16、ue of testing becomes especially ambiguous- and ethically complicated- when there is no way to prevent or treat disease, as in the case of early-onset Alzheimers, which often strikes before the age of 50. or Huntingtons.Today only about 5 Percent of people who are at risk for Huntingtons-which is ca
17、used by a single gene and leads to a progressive loss of physical control and mental acuity-take the test. Many are worried that genetic testing will put their health insurance or job security at risk. While there have been few documented cases of discrimination, nobody can say for sure what will ha
18、ppen as more disease genes are discovered and more Americans sign on for predictive testing. States have a patchwork of regulations in place, but what needs to happen now, experts say, is for Congress to pass the Genetic Information Nondiscrimination Act, which would put a federal stamp of approval
19、on keeping genetic information safe.Moreover, some people cant live with uncertainty. Stephanie Vogt knew Huntingtons ran in her family-her grandfather and his three brothers all died of complications of the disease-and she wanted to find out where she stood. “As soon as 1 found out there was a test
20、. I just had to do it,“ she says. In August 2000, after comprehensive genetic counseling, Stephanie, her sister, Victoria, and their mother, Gayle Smith, learned her results: positive. “It was like a scene out of The Matrix, where everything freezes and struts again,“ says Stephanie, now 35 and sing
21、le.Scientific revolutions must be tempered by reality. Genes arent the only factors involved in complex diseases-lifestyle and environmental influences, such as diet or smoking, are too. And predictions about new tests and treatments may not come to pass as fast as researchers hope-they may not come
22、 at all. Still, its hard not to get excited about the future, especially when you consider the medical competition now underway.（分数：70.00）(1).Pauline Gross felt scared because she thought she would die of_.（分数：7.00）A.strokeB.cancerC.SARSD.AIDS(2).Genetic testing can be used to decide whether a patie
23、nt has the inheritable gene mutation by peering into their_.（分数：7.00）A.blood cellB.lung cellC.liver cellD.DNA(3).The major purpose of genetic testing in medication is to_.（分数：7.00）A.predict the death rate of inheritable diseaseB.predict: a patients response to medicationC.find out the biological sou
24、rce and fix the problemD.guide safe and appropriate treatment(4).What have Christopher Ross experimental results revealed to us?（分数：7.00）A.Those inheritable diseases may be cured through genetic testing.B.Those inheritable diseases may be predicted through genetic testing,C.Those inheritable disease
25、s may be prevented through genetic testing.D.Those inheritable diseases may be controlled through genetic testing.(5).How many people with breast cancer are inherited from family tree?（分数：7.00）A.5 to 10 percent.B.10 percent.C.About 15 percent.D.5 percent.(6).Couples planning to have children can tak
26、e prenatal genetic tests to know_.（分数：7.00）A.whether their babies are genetically healthy or notB.whether they can have a babyC.when their babies will come into the worldD.whether their babies are boy or girl babies(7).According to the passage, what is Wendy Uhlmanns attitude toward genetic testing?
27、（分数：7.00）A.She is indifferent to it.B.She does not agrees with it at all.C.She has no idea about it.D.She has some doubts about it.(8).Many choose not to take the genetic testing because they worried that it will risk their_.（分数：7.00）填空项 1:_(9).In August 2000, Stephanie Vogt learned she got the dise
28、ase of_.（分数：7.00）填空项 1:_(10).From the last paragraph, we know many, factors involved in complex diseases, such as gene, lifestyle and_.（分数：7.00）填空项 1:_三、BPart Listenin(总题数：3，分数：105.00)Questions 11 to 18 are based on the conversation yon have just heard.（分数：56.00）A.Dana agrees with her.B.Dana likes t
29、he food.C.Dana likes to put on weight.D.Dana must be unhappy.A.It is rainy.B.It is sunny.C.It is fine.D.It is cloudy.A.The play is seldom delayed to start.B.The play will start twenty minutes later.C.The newspaper is seldom wrong.D.They probably have to continue to wait.A.He didnt have enough moneyB
30、.Radios of all, brands were sold out then.C.He couldnt get the right brand of radio.D.The store will sell the radio tomorrow.A.It will take at least three, week, to finish the test.B.The test will be more difficult than they expect.C.They still have time to prepare for it.D.The test will be more dif
31、ficult than they expect.A.Go with the woman for a drink.B.Drink what he has brought with him.C.Continue with his work until lunchtime.D.Ask the woman to get him some soft drink.A.He will write a letter to another company.B.He has received many job offers.C.He hasnt accepted the job offer.D.He will l
32、et the woman have the job.A.She will have a drink while she waits.B.She will help the man with the work.C.She will get some coffee for the man.D.She will go out first and get her car.BQuestions 19 to 21 are based on the conversation yon have just heard./B（分数：21.00）A.Tennis sets.B.Computer and TV set
33、.C.Bookcase and book shelf.D.Refrigerator and kitchen stuff.A.Give them to the second and third year students for free.B.Sell them to the second-hand bookshop.C.Advertise them in the student newspaper for sale.D.Advertise them on the university notice boards.A.It may not pay well.B.It may not come o
34、n time.C.It may not take your goods.D.It may charge the quote.BQuestions 22 to 25 are based on the conversation yon have just heard./B（分数：28.00）A.Love for beauty and a desire to impress other people.B.A desire to express oneself and a display of ones wealth.C.Individual taste and love for beauty.D.I
35、ndividual taste and a desire to express oneself.A.They may be homesick and feel insecure.B.They may try to attract other peoples attention.C.They are either cold or sick.D.They want to protect themselves from physical injuries.A.They prefer white.B.They prefer red.C.They prefer yellow.D.They prefer
36、gray.A.Reporter and fashion designer.B.Teacher and student.C.Shop assistant and customer.D.Husband and wife.四、BSection B/B(总题数：3，分数：70.00)BQuestions 26 to 28 are based on the passage you have just heard./B（分数：21.00）A.Solar energy.B.Synthetic fuel.C.Alcohol fuel.D.Electricity power.A.Air traffic cond
37、itions.B.Road conditions.C.New traffic rules.D.Traffic jams on highways.A.Arrive early for boarding.B.Carry little luggage.C.Undergo security checks.D.Arrive late for boarding.BQuestions 29 to 31 are based on the passage you have just heard./B（分数：21.00）A.He feels funny.B.He feels angry.C.He feels ex
38、cited.D.He feels sad.A.The newcomers dont like the new environment shortly after their arrival.B.The newcomers begin to hate the city, the country in the new culture.C.The newcomers begin to enjoy their life more after they leave the country,D.The newcomers begin to adjust to their surroundings and
39、enjoy their life.A.The people who had no hobbies in their own culture.B.The people who were not active and successful in their own culture.C.The people who had high position in their own culture.D.The people who never had any difficulties in their own culture.BQuestions 32 to 35 are based on the pas
40、sage you have just heard./B（分数：28.00）A.In the 17th century.B.In the 1Sth century.C.In the 18th century.D.In the 16th century.A.Because of the beautiful garden in front of it.B.Because of its old style of architecture.C.Because it was at the sea side.D.Because it was the only modern building there.A.
41、To welcome the tourists.B.To make money.C.To keep the tourists away.D.To attract the tourists.A.In order to have more peace.B.In order to earn more money.C.In order to welcome more visitors.D.In order to have a bigger garden.五、BSection C/B(总题数：1，分数：77.00)The need for birth control methods has develo
42、ped fairlyU (36) /U, with the desire among many women to be able toU (37) /Uwhen they want to have a baby. At the same time there is a growingU (38) /Uof the problem of a rapidly increasing world population.This problem of aU (39) /Uworld population is largely the result ofU (40) /U medical skills,
43、which haveU (41) /Uthe death rate and at the same time raised the birth rate by increasing live births and the number of babies whoU (42) /Uearly childhood. There is a growingU (43) /Uthat food production cannot keep pace with these increase, the result of which is that in some countries people are
44、already starving to death. This problem is further complicated by the fact that in places like America and Europe, we obtain by trade and consume far more food and resources like oil than, say, the average India, U(44) /U.World population is rising at rate of two percent a year; this means an additi
45、on of 70 million people a year to the present population of more than 3 500 million. U(45) /U. The fastest growing region is Latin America which includes South and Central America and the Caribbean, while Africa and Asia closely follow Latin America. However, U(46) /U. （分数：77.00）(1).（分数：7.00）填空项 1:_
46、填空项 1:_填空项 1:_填空项 1:_填空项 1:_填空项 1:_填空项 1:_填空项 1:_填空项 1:_填空项 1:_填空项 1:_六、BPart Reading (总题数：1，分数：90.00)The ability to laugh at your own weaknesses and blunders (失误) has long been recognized as a sign of maturity. And yet this is one of the most difficultU (47) /Uof your sense of humor to develop.Osca
47、r Wilde once offered aU (48) /Uinsight about the way we live our lives when he said that “Life is too important to be taken seriously.“ I dont think he meant you dont have to take yourU (49) /U, promises, work, etc. seriously. He didnt mean that its OK to live life with noU (50) /UI think he meant that the quality of our life suffers when weU (51) /Ueverything in a serious manner. We are no longerU (52) /U, cheerful and spontaneous as when we were kids when we take everything so seriously.I think the key here is to take your work and yo
