1、American National Standardfor Hazardous Workplace Chemicals Hazard Evaluation andSafety Data Sheet andPrecautionary Labeling PreparationANSI Z400.1/Z129.1-2010ANSI Z400.1/Z129.1-2010ANSIZ400.1/Z129.1-2010Revision, redesignation, and-consolidation ofANSI Z400.1-2004 andANSI Z129.1-2006American Nation
2、al Standardfor Hazardous Workplace Chemicals Hazard Evaluation andSafety Data Sheet andPrecautionary Labeling PreparationSponsorAmerican Chemical CouncilApproved May 28, 2010 American National Standards Institute, Inc.Approval of an American National Standard requires review by ANSI that therequirem
3、ents for due process, consensus, and other criteria for approval havebeen met by the standards developer.Consensus is established when, in the judgement of the ANSI Board ofStandards Review, substantial agreement has been reached by directly andmaterially affected interests. Substantial agreement me
4、ans much more thana simple majority, but not necessarily unanimity. Consensus requires that allviews and objections be considered, and that a concerted effort be madetowards their resolution.The use of American National Standards is completely voluntary; theirexistence does not in any respect preclu
5、de anyone, whether he has approvedthe standards or not, from manufacturing, marketing, purchasing, or usingproducts, processes, or procedures not conforming to the standards.The American National Standards Institute does not develop standards andwill in no circumstances give an interpretation of any
6、 American NationalStandard. Moreover, no person shall have the right or authority to issue aninterpretation of an American National Standard in the name of the AmericanNational Standards Institute. Requests for interpretations should beaddressed to the secretariat or sponsor whose name appears on th
7、e titlepage of this standard.CAUTION NOTICE: This American National Standard may be revised orwithdrawn at any time. The procedures of the American National StandardsInstitute require that action be taken periodically to reaffirm, revise, orwithdraw this standard. Purchasers of American National Sta
8、ndards mayreceive current information on all standards by calling or writing the AmericanNational Standards Institute.American National StandardPublished byAmerican National Standards Institute, Inc.25 West 43rd Street, New York, NY 10036Copyright 2010 by American Chemical Council (ACC)All rights re
9、served.No part of this publication may be reproduced in anyform, in an electronic retrieval system or otherwise,without prior written permission of the publisher.Printed in the United States of AmericaiContentsPageForeword viiIntroduction .xi1 General 11.1 Safety Data Sheet (SDS). 11.2 Precautionary
10、 labeling . 12 Scope, purpose and application. 22.1 Scope. 22.2 Purpose 22.3 Application . 3 2.3.1 Audience 32.3.2 Content and organization. 32.3.3 Hazard evaluation and communication process flow. 33 Hazard evaluation 63.1 Definition of a hazard. 63.2 Collecting the information 63.3 Evaluating haza
11、rds 74 Physical hazards 84.1 Definition of a physical hazard. 84.2 Physical hazard criteria 84.2.1 Fire hazard chemical 84.2.1.1 Flammability hazards. 84.2.1.1.1 Gases. 84.2.1.1.2 Liquids 94.2.1.1.2.1Static accumulating flammable liquids. 104.2.1.1.3 Solids . 114.2.1.1.4 Flammable aerosols (flammabl
12、es in self-pressurized containers). 114.2.1.2 Oxidizer 114.2.1.3 Organic peroxide 124.2.1.4 Pyrophoric chemical. 124.2.2 Pressure-generating chemical . 124.2.3 Water reactive chemical. 124.2.4 Compressed gas 124.2.5 Cryogenic liquid . 134.2.6 Unstable reactive 134.2.7 Corrosive to metal 134.3 Physic
13、al hazard evaluation 134.3.1 Sources of information. 144.4 Statements of physical hazards. 144.5 Physical hazard precautionary statements 14iiPage5 Health hazards. 155.1 Definition of a health hazard 155.1.1 Immediate health hazard criteria . 155.1.1.1 Corrosive . 155.1.1.2 Irritant. 155.1.1.3 Inhal
14、ation . 165.1.1.3.1 Highly toxic (poison) by inhalation . 165.1.1.3.2 Toxic by inhalation . 165.1.1.3.3 Simple asphyxiants 165.1.1.3.4 Additional information for inhalation toxicity. 165.1.1.4 Dermal . 175.1.1.4.1 Highly toxic (poison) by skin contact 175.1.1.4.2 Toxic by skin contact . 175.1.1.4.3
15、Harmful by skin contact . 175.1.1.5 Oral 175.1.1.5.1 Highly toxic (poison) by ingestion 175.1.1.5.2 Toxic by ingestion 175.1.1.5.3 Harmful by ingestion 175.1.1.5.4 Aspiration. 175.1.2 Allergic reactions (sensitizer). 185.1.3 Delayed health hazard criteria . 185.1.3.1 Target organ effects. 185.1.3.2
16、Carcinogenicity/Cancer 185.1.3.3 Reproductive, developmental and teratogenic effects. 195.1.3.4 Mutagenicity. 195.2 Health hazard evaluation . 205.2.1 Sources of information. 205.3 Evaluating health hazards for mixtures 225.4 Statements of health hazards 225.4.1 Health hazards. 235.4.1.1 Precautiona
17、ry labeling for immediate health hazards 235.4.1.2 Precautionary labeling for allergic skin and respiratory reactions 235.4.1.3 Precautionary labeling for delayed health hazards 235.4.1.3.1 Carcinogenicity 245.4.1.3.2 Reproductive/Developmental/Teratogenic effects . 265.4.1.3.3 Mutagenicity. 275.4.1
18、.4 No significant adverse health effects . 275.5 Health hazard precautionary statements . 276 Environmental hazards 286.1 Definition of an environmental hazard . 286.2 Environmental hazard criteria 286.3 Environmental hazard evaluation 286.3.1 Sources of information 286.4 Statements of environmental
19、 hazards . 296.5 Environmental hazard precautionary statements 30iiiPage7 Hazard communication principles 318 Safety data sheets (SDS). 328.1 Introduction 328.2 SDS communication principles 328.2.1 Layout and design 328.2.2 Reading level and comprehension. 338.3 SDS Organization 348.3.1 What is the
20、material and what do I need to know immediately in an emergency?. 348.3.2 What should I do if a hazardous situation occurs?. 348.3.3 How can I prevent hazardous situations from occurring? 348.3.4 Is there other useful information about this material? 348.4 Evaluation of the SDS 348.4.1 Internal cons
21、istency . 348.4.2 Headers/Footers 358.4.3 Document identifier 358.4.4 Review/Preparation date 358.4.5 Page and section numbers 358.4.6 Units of measure 358.4.7 No blank data fields 368.5 Revision of the SDS 379 Sections of the safety data sheet (SDS) 379.1 Section 1: PRODUCT AND COMPANY IDENTIFICATI
22、ON 379.2 Section 2: HAZARDS IDENTIFICATION 389.2.1 Emergency overview 389.2.2 OSHA Regulatory status 399.2.3 Potential health effects. 409.2.4 Potential environmental effects 419.3 Section 3: COMPOSITION/INFORMATION ON INGREDIENTS . 429.4 Section 4: FIRST AID MEASURES. 439.4.1 First aid procedures .
23、 439.4.2 First aid statement 449.4.2.1 First aid for exposure to eyes and skin 449.4.2.2 First aid for inhalation. 459.4.2.3 First aid for ingestion 459.4.2.3.1 When the induction of vomiting is warranted . 459.4.3 Note to physicians 469.4.3.1 Antidotes 469.5 Section 5: FIRE FIGHTING MEASURES 479.5.
24、1 Flammable properties 489.5.2 Extinguishing media . 489.5.2.1 Suitable extinguishing media . 489.5.2.2 Unsuitable extinguishing media . 509.5.3 Protection of firefighters . 509.5.3.1 Specific hazards arising from the chemical 509.5.3.2 Protective equipment and precautions for firefighters 51ivPage9
25、.6 Section 6: ACCIDENTAL RELEASE MEASURES . 529.6.1 Personal precautions . 529.6.2 Environmental precautions 529.6.3 Methods for containment . 529.6.4 Methods for clean-up . 529.6.5 Other information . 539.6.6 Spill or leak statements by type of chemical 539.7 Section 7: HANDLING AND STORAGE . 559.7
26、.1 Handling. 559.7.2 Storage 579.8 Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION. 589.8.1 Exposure guidelines 589.8.2 Engineering controls 599.8.3 Personal protective equipment (PPE) 599.8.3.1 Eye/face protection 609.8.3.2 Skin protection . 609.8.3.3 Respiratory protection 609.8.3.4 General hygie
27、ne considerations 619.9 Section 9: PHYSICAL AND CHEMICAL PROPERTIES. 619.10 Section 10: STABILITY AND REACTIVITY 639.10.1 Reactivity . 639.10.2 Possibility of hazardous reactions . 639.10.3 Chemical stability. 639.10.4 Conditions to avoid 649.10.5 Incompatible materials. 649.10.6 Hazardous decomposi
28、tion products 649.11 Section 11: TOXICOLOGICAL INFORMATION . 649.12 Section 12: ECOLOGICAL INFORMATION . 679.13 Section 13: DISPOSAL CONSIDERATIONS . 709.14 Section 14: TRANSPORT INFORMATION 719.14.1 Basic shipping description . 729.14.2 Additional information 729.15 Section 15: REGULATORY INFORMATI
29、ON 739.16 Section 16: OTHER INFORMATION 7610 Labels and labeling 7810.1 Introduction 7810.2 Scope. 7810.3 Labeling communication principles 7910.3.1 Comprehension . 7910.3.2 Layout and design . 7910.3.2.1 Layout 7910.3.2.2 Color 8010.3.2.3 Type size and style 8010.4 Elements of a label 80vPage10.4.1
30、 Importer/Distributor requirements 8110.5 Durability of a label. 8110.6 Revision of precautionary labeling . 8111 Preparing precautionary labeling . 8211.1 Product identification 8211.2 Component identification 8211.2.1 Trade secrets . 8211.3 Signal word 8211.3.1 Poison symbol 8311.4 Statement of ha
31、zard. 8311.5 Name, address and telephone number 8311.6 Precautionary statements 8311.7 References to additional labeling/other documents . 8412 Review of documents. 8413 Tables of hazard criteria and precautionary label text . 85Table A Physical Hazards (see Section 4.2) 87Table B Health Hazards: Sk
32、in Corrosion/Irritation (see Sections 5.1.1.1 and 5.1.1.2) . 91Table C Health Hazards: Eye Corrosion/Eye Irritation (see Sections 5.1.1.1 and 5.1.1.2). 93Table D Health Hazards: Respiratory Irritation (see Sections 5.1.1.1 and 5.1.1.2). 94Table E Health Hazards: Sensitization (see Section 5.1.2) 95T
33、able F Health Hazards: Inhalation Toxicity (see Section 5.1.1.3) 96Table G Health Hazards: Dermal Toxicity (see Section 5.1.1.4) 98Table H Health Hazards: Oral Toxicity (see Section 5.1.1.5) . 100Table I Additional hazard warning statements . 103Part 1 - Examples of optional hazard warning statement
34、s 103Part 2 - Environmental hazard warning statements 109Table J Additional optional precautionary measures statements. 11114 Resources 12314.1 American National Standards 12314.2 Other standards . 12314.3 Regulatory standards . 12314.4 References and other useful publications 123viPageAnnexesA Exam
35、ples of SDSs and labels . 128B Background: The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) 157C Preparation resources document. 173D Glossary. 181viiForeword (This foreword is not part of American National Standard ANSI Z400.1/Z129.1-2010.)ANSI Z400.1/Z129.1-2010, A
36、merican National Standard for Hazardous WorkplaceChemicals - Hazard Evaluation and Safety Data Sheet and Precautionary LabelingPreparation, was developed by a technical committee of the American ChemistryCouncil (ACC) and was submitted for approval under ACCs ANSI-approved canvassmethod operating pr
37、ocedures. The need for consistent precautionary labeling was recognized in 1944, when theManufacturing Chemists Association (which later became the Chemical Manufactur-ers Association CMA and then the American Chemistry Council ACC) establishedthe Labels and Precautionary Information (LAPI) Committe
38、e. The LAPI Committeedeveloped the first published industry guide to precautionary labeling for hazardouschemicals titled “A Guide for the Preparation of Warning Labels for HazardousChemicals“ or Manual L-1. This was converted to American National Standard forHazardous Industrial Chemicals - Precaut
39、ionary Labeling (ANSI Z129.1) in 1976. A companion document, American National Standard for Hazardous IndustrialChemicals - Material Safety Data Sheets - Preparation (ANSI Z400.1-1993), was de-veloped in recognition of the need for technical guidance for preparing consistent,clear and complete Mater
40、ial Safety Data Sheets (MSDSs). ANSI Z400.1/Z129.1-2010 was developed in recognition that ANSI Z129.1 and ANSIZ400.1 were both hazard communication guidance documents that were generallyused together, by the same audience, and had somewhat similar content. This stan-dard is the result of the merging
41、 of ANSI Z129.1 and ANSI Z400.1 into one compre-hensive standard on hazard communication. It is organized to reflect the typical workflow of hazard communicators. In addition to the merging of ANSI Z129.1 and ANSI Z400.1, several other significantchanges were made to the content of this document: -
42、References to “industrial chemicals“ have been changed to “workplacechemicals“ to more accurately reflect the scope of the OSHA Hazard Commu-nication Standard and therefore the scope of this Standard. - Information was added for three additional physical hazards - static accumu-lating flammable liqu
43、ids, corrosive to metals, and flammable aerosols. - The recommendations for First Aid have been updated to reflect the mostcurrent clinical practices. - Aspiration hazard now includes a signal word recommendation. Work on this standard was conducted during 2008 - 2009. In late 2009, OSHA pub-lished
44、the Hazard Communication Proposed Rule (Federal Register, Vol. 74, No.188, Pages 50280 - 50549) for the adoption of the Globally Harmonized System(GHS). The question was raised whether to publish a revised ANSI standard withoutadditional alignment with GHS as originally scheduled or to delay publica
45、tion until af-ter GHS is officially adopted by OSHA. After a careful evaluation, the committee de-cided to publish the standard as originally scheduled for the following reasons:- It will likely be at least eighteen months following the publication of OSHAsNPRM before it is enacted. Following GHS ad
46、option by OSHA, there will be atleast a three year transition period. This is a significant period of time duringwhich the revised ANSI standard will still provide value. - We believe the new merged standard is a valuable tool that is useful nowand should not be delayed.viii- The revised Standard in
47、cludes information on static accumulating flammableliquids, and emphasis on combustible dust. These changes are in response torecommendations made to the committee by the U.S. Chemical Safety Board(CSB). Additional information is also provided on corrosive to metals.The committee recognizes that OSH
48、As implementation of the GHS is likely to occurwithin the next few years. We have incorporated some GHS concepts throughout thetext of the Standard, and have enhanced the information included in the GHS annex.We will monitor developments and will revise the Standard earlier than the regularlyschedul
49、ed five years if necessary. This Standard contains four annexes, all of which are informative and are not consid-ered part of the Standard. Suggestions for the improvement of this Standard are welcome and will be consid-ered for subsequent revisions. They should be addressed to the American ChemistryCouncil, 700 2nd Street, NE, Washington, DC 20002. The following organizations, recognized as having an interest in the standardizationof precautionary labeling of industrial chemicals, were contacted prior to the approvalof this standard. Inclusion in this list does not necessarily im
