GOST 32429-2013 Testing of chemicals of environmental hazard 21-day Fish Assay A Short-Term Screening for Oestrogenic and Androgenic Activity and Aromatase Inhibition《环境危险化学品测试 21天.pdf

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1、 , () INTERSTATE COUNCIL FOR STANDARDIZATION, METROLOGY AND CERTIFICATION (ISC) 32429 2013 , : 21- (OECD, Test No230:2009, IDT) 2014 32429-2013 II , 1.092 . 1.22009 . , . , , , 1 , , ( ) 2 3 , 5 2013 . 61 ) : 3166) 004 97 3166) 004 97 AZ AM BY KG MD RU UZ UA 4 OECD Test No 230 21-day Fish Assay: A S

2、hort-Term Screening for Oestrogenic and Androgenic Activity, and Aromatase Inhibition ( 230 : 21- ). (en). (IDT) 5 22 2013 790- 324292013 1 2014 . 6 324292013 III , . ( ) . , , 2014 , 32429-2013 IV 1 . 1 2 1 3 1 4 2 5 . 2 6 . 3 7 . 4 8 6 ( ) 9 B ( ) 11 C ( ) 12 D ( ) 13 E ( ) 14 F ( ) 16 F ( ) 17 H

3、( ) 19 I ( ) , 27 J ( ) 28 30 324292013 V , , , , . 21- , , ( (Pimephales promelas), (Oryzias latipes) (Danio rerio); , . OECD 229 , , . OECD 229 , , . , , . 324292013 1 , : 21- Testing of chemicals of environmental hazard. 21-day Fish Assay: A Short-Term Screening for Oestrogenic and Androgenic Activity, and Aromatase Inhibition 20140801 1 in vivo ( ), (21 ). 21- , , . (VTG) . , , . . , ( ) , . 2 : 2.1 : . 2.2 (VTG): , . 2.3 (M): 10 % LC 50 . 2.4 HPG: 2.5 : . 3 3.1 (VTG) , , , . , ; . 3.2

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