1、 , () INTERSTATE COUNCIL FOR STANDARDIZATION, METROLOGY AND CERTIFICATION (ISC) ISO 29621 2013 (ISO 29621:2010, IDT) 2014 ISO 296212013 II , - 1.092 . 1.2 2009 . -, . , , , 1 - ( ) - ( ) - , 4 2 3 , (- 59- 27 2013 .) : ( 3166) 00497 ( 3166) 00497 AM BY MD - RU UZ 4 22 2013 . 2078- 01 2015 . 5 ISO 29
2、621:2010 Cosmetics Mi-crobiology Guidelines for the risk assessment and identification of microbiologically low-risk products (. . ). ISO/TC 217 (ISO). : 3.2.4 , , , 009/2011 - -. (en). , - , - . (IDT) 6 ISO 296212013 III - , . () - - . , , 2014 -, - ISO 296212013 IV , . , , - . -, , , . , , . - , /
3、 ; , . , . - , , - . / , , . . - - , . - . , , - , . , , -, , , - . (GMP) (. ISO 22716) , - . - ( ), , - / . - . ( ) , . - , GMP, , , . , , , -. - , , - - . ISO 296212013 1 Cosmetics. Microbiology. Guidelines for the risk assessment and identification of microbiologically low-risk products 2015 01 0
4、1 1 - , , , / . 2 . 2.1 (risk): . ISO 73:2009, 1.1. : - ; - , - , , ISO 18415, ISO 18416, ISO 22717, ISO 22718 ISO 21150. 2.2 (risk assessment): , (2.3) (2.4). ISO 73:2009, 3.4.1. 2.3 (risk analysis): (2.1) . ISO 73:2009, 3.6.1. 2.4 (risk evaluation): (2.3) (2.5) , (1.1) / . ISO 73:2009, 3.7.1. 2.5
5、(risk criteria): , - (2.1). ISO 73:2009, 3.3.1.3. 2.6 (microbiologically low-risk products): -, / (- ) . 1 -, / . 2 , , - . 3 , , . ISO 296212013 2 3 3.1 , , - . - , , -. 3.2 3.2.1 - - , . - , - / . - , -. - , - , , . . - , , . 3.2.2 , aw, , -. , , . - . , aw. - : )( 21 20w nn nppa , (1) p ; p0 ; n1 ; n2 . , , 1,00 (aw ). aw. aw . - ( aw), - . , , . aw, . aw - , . aw -, - , . . aw - . - aw 0,90. aw 0,60 1. , . ISO 296212013 3 1 , aw, 2 aw 0,90 Pseudomonas species 0,96 Enterobacteriacae 0,93 Staphylococcus aureus 0,86 0,70 0,60 , , -, pH . - , - . , ,
