GOST 32437-2013 Testing of chemicals of human hazard Chronic toxicity studies《人类危险化学品测试 慢性毒性研究》.pdf

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1、 , () INTERSTATE COUNCIL FOR STANDARDIZATION, METROLOGY AND CERTIFICATION (ISC) 32437 2013 (OECD, Test No452:2008, IDT) 2014 324372013 II , - 1.092 . - 1.22009 . -, . , -, , 1 - ( - ); - , , - ( ) 2 3 , ( 61- 5 2013 .) : ( 3166) 004 97 ( 3166) 004 97 AM BY KG MD RU TJ - 4 OECD, Test 452 Chronic Toxi

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3、011 -. - , - . , , : , ; ; in vitro in vivo ; - ; (Q)SAR - ; (- , ) , - . 28 / 90 3, 4. - . , - . - , - . - , (NOAEL), - . . - , 5 , , , , 5. - . . , , . - . -, . . - . 1 324372013 2 2 -: 2.1 : (dose) . (, ), (/). 2.2 (Dosage): , , . 2.3 , (NOAEL): (Identification of a no-observed-adverse-effect lev

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